Approaches and infrastructure
Models and Methods for Mapping Gut Mucosal Integrity and Function
Organoid TechnologyWe use advanced intestinal organoid models derived from patient tissues. These three-dimensional cultures faithfully replicate the cellular and functional properties of the human gut, including epithelial differentiation and barrier formation. While the direct co-culture...Learn moreUnderstanding the Role of Bile Salt Signaling in Gut and Liver Health
ApproachOur research team is dedicated to understanding the role of bile salt signaling in maintaining the health of the intestine and liver. We also explore how disruptions in this signaling pathway contribute to various diseases....Learn moreHarnessing Patient-Derived Materials to Unravel Cancer Cachexia
Understanding cancer cachexia -a complex syndrome marked by severe weight and muscle loss- requires research models that closely reflect the human condition. By utilizing patient-derived materials, we can directly investigate the mechanisms driving cachexia, paving...Learn more
